Physical and chemical properties
Melting point: ＞ 300 ℃, relative density: 1.89g/cm, 2. Solubility: practically insoluble, appearance: almost white crystalline powder
Description of use
1. Hypoxanthine is a collection of biological fermentation and chemical synthesis of nucleoside antiviral drugs 2. Hypoxanthine can help iron absorption and intellectual development 3. It is used as a raw material for mercaptopurine and azathioprine
Preparation method
2-mercapto-4-amino-6-hydroxypyrimidine was obtained by cyclization of ethyl cyanoacetate with sodium ethoxide and thiourea, and then 6-hydroxypurine was prepared by nitrification, reduction, elimination and cyclization