Uracil is the specific base of RNA, which is equivalent to thymine (T) in DNA. It is one of the four bases of RNA. It replaces thymine in DNA during DNA transcription and matches with adenine. Thymine (T) is obtained by methylation of uracil.
Character: white or light yellow acicular crystal.
Solubility: soluble in hot water, dilute ammonia, slightly soluble in cold water, insoluble in ethanol and ether.
Decomposition temperature: 294 ℃ (213 ℃ is also recorded); Not resistant to alkali.
Toxicity: Intravenous injection in mice is toxic, but oral and dermal toxicity is small. It has little toxicity to fish, and young carp have no interference in 10mg/L solution.
Uracil is the specific base of RNA, which is equivalent to thymine (T) in DNA. In the process of DNA transcription, DNA is decompressed by helicase in the nucleus, and then paired with free base pairs to form a single-stranded RNA, which becomes messenger RNA (mRNA). In this process, the base pairing principles are: A-U, C-G, T-A, G-C. One of the pyrimidine bases, which is a component of RNA together with cytosine. It is also contained in uridine diphosphate glucose and other important precursors of polysaccharides. It shows specific ultraviolet absorption (259 nanometers maximum). The main difference between RNA and DNA is the difference in sugar composition. RNA contains uracil and DNA contains thymine.
Description of use
Uridine is a drug, such as anti-giant red blood cell anemia, to treat liver; Cerebrovascular; Cardiovascular and other diseases are also manufacturing fluorouracil (S-FC); Deoxynucleoside; Iodine glycoside (IDUR); Bromoside (BUDR); Fluoroside (FUDR) is the main raw material of drugs.